Sitting one point shy of table-topping Bayern Munich, BVB will be wary of the threat posed by Gladbach, who have been wildly unpredictable throughout this season.
Borussia Dortmund ensured that Bayern Munich will not waltz their way to an 11th successive Bundesliga title as they kept the pressure on the perennial champions with a statement victory over Wolfsburg last time out.
Karim Adeyemi and Jude Bellingham both bagged a brace in the rout, while Sebastien Haller and Donyell Malen completed the scoring, meaning that Malen has netted seven goals across the previous seven league games.
Sunday's victory was Dortmund's 10th straight Bundesliga win at Signal Iduna Park, while BVB have avoided defeat in each of their last 13 home league games, securing 12 victories to keep pace with Bayern.
In truth, Edin Terzic's men have been in excellent form since returning from the winter break, as they have suffered a solitary defeat in 16 league matches this side of the World Cup, taking 39 points from a possible 48.
Having scored 41 goals across their 10-game winning streak on home soil – netting at least four goals on seven occasions in that time – Borussia Dortmund are not likely to be kept quiet by Saturday's visitors.